Hard to say so far tbh. I haven't really noticed a massive difference from prior years in terms of general game play. The updated database and list of wonderkids etc is canny but you could probably find an updated db for FM21 with all that on anyways and save a few quid.
I think the AI cottons on to your tactics a lot faster in the latest version. Once upon a time I'd only need to tweak the tactics every 9 months or so in older FM games. Now I feel like I need to get actual coaching badges to play the fucker because my tactics are sussed every 3 months.
Save to say I sacked off my Newcastle save despite having a best XI of:
GK Diego Costa
RB Livramento (who becomes a beast if you play him enough)
CB Diomande
CB Botman
LB DiMarco
CDM Bruno
CM Tonali
CM Joelinton
RW Raphinha
CF Osimhen
LW Musiala
^This team, despite my tactics that won the domestic cup double, and got to the final of the champions league was suddenly drawing at home to newly promoted Luton (who were in administration and had those literal greyed out, shite players you can't sign making up squad numbers). I lost the dressing room because I couldn't pick one foreign player for the champions league squad, and the cunts downed tools.
I booted up a new game as England manager, and have a 100% win record so far with those same tactics. I'm going to let Howe do his thing for a bit and when he gets pied off I'll swoop in, like a Geordie white knight and lead them back to the promised land of mid-table mediocrity.